Thrombolytic Therapy (TPA)

(Treatment to break up blood clots)

Home > Procedures > Thrombolytic Therapy (TPA)

Thrombolytic therapy is the use of drugs to dissolve blood clots. The therapy is often also called tPA – tissue plasminogen activator – for a commonly used thrombolytic, or clot-busting, agent. TPA is administered through an intravenous (IV) line into the bloodstream.

Patient Advice

Overall Rating
average of all patients
Pain is 6 of 10
Inconvenience is 7 of 10

About the rating

Preparation for Thrombolytic Therapy (TPA):
“Get a second opinion, i.e., ask at least a few doctors about the right thrombolytic therapy for you. In addition to TPA, there are other medication options with various risk/benefit profiles.”

After Thrombolytic Therapy (TPA):
“Report any discomfort to your doctor.”

“Ask questions about after-care.”


Patient Stories

Thrombolytic Therapy (TPA)

During my second cycle on chemo, I woke up one morning and my arm was 1.5 times as big as the other: it was swollen, bright white and painful to the touch. I was rushed into the emergency room with a blood clot. Read More

Jonny, male, 33, Michigan


Areas of Interest

Sign up for the latest research news and stories. Share your experience and help others.


Immerman Angels

One-on-one Cancer Support

Connecting cancer fighters, survivors and caregivers.

Learn more

Research News

No Research News